The parasite’s main hosts are the humans. The Anopheles mosquito is just but a secondary host. The mosquitoes first get infected by ingesting a blood meal from an infected human and they like to feed at night.
The transmission process is quite complex. The Plasmodium sporozites are found in the salivary glands of the mosquitoes. When an infected mosquito bites a person, the sporozites in the mosquito’s saliva enters the blood stream or lymphatic system and move to the liver. In the liver, the sporozites are well protected from the immune system. They also grow and multiply while in there. Their multiplication leads to the rapture of liver cells and escape of the parasite into the blood stream once again. The parasite feeds on hemoglobin and other materials in the red blood cells and this is what damages the cells. At this stage, Malaria symptoms begin to be manifested. It usually takes about 1-4 weeks after infection for the first symptom to appear.
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